Posts

Showing posts from February 22, 2024

New vaccine for Dengue is coming .. shortly “Butantan - DV”

  New vaccine for Dengue is coming .. shortly     “Butantan - DV” Interim results of a live attenuated single dose Dengue vaccine is highly promising. Phase III trials ongoing in Brazil for five years , analysis at the end of 2 years are published in NEJM this month . 🔴Situation of dengue worldwide  & India Almost 300 Million cases of dengue worldwide.In India Dengue and Leptospirosis constitute major morbidity and mortality even now Mortality was .much high before 2009 Since the awareness ,early detection and WHO treatment guidelines implemented we could bring down the mortality .Even though dengue vaccines were available in other countries so far we are yet to go for it .Main reason , there were safety concerns about the vaccines which were used in some countries.    🔴 Vaccines available now for Dengue  Out of many vaccines in phase III trials two are in the market       🧁 Dengvaxia ( CYD-TDV) a live attenuated vaccine containing all the four strains (I,II, III,IV) of the vi